A Patient with Synchronous Follicular (Hurthle Cell), Papillary, and Medullary Thyroid Carcinomas: A Case Report with Literature Review on Possible Incidence and Pathogenesis

This case report is the fourth case documented of a patient with synchronous Follicular, Papillary, and Medullary Thyroid Carcinoma. There have been several case series in the last two decades that include either concurrent papillary-medullary or follicular-medullary thyroid carcinoma, but only three cases documented for all three of these types of thyroid carcinomas occurring in the same patient. There has been conflicting research on whether the pathogenesis of such synchronicity is coincidental or molecular/genetically linked. Advances in molecular/genetic detection in the last five years has elucidated new evidence that synchronous occurrence of MTC, PTC, and FTC may be coincidental.